From October 28 to November 2, 2018 the American Chamber of Commerce (AmCham) Kenya, in collaboration with the State Department for Trade and with the support of the Commercial Service of the U.S. Embassy in Kenya, held a trade mission to the U.S. covering New York and Washington DC to promote trade and investment opportunities in Kenya under the Big Four Agenda. The mission coincided with the launch of the first non-stop Kenya Airways flight to New York and comprised of one business and investment briefing forum, one bi-lateral and one tri-lateral meeting, business-to-government engagements and a networking reception. This report provides a background on the mission, highlights of the key activities that took place and the outcomes and learnings from the mission.